CyberCom investigates a terrorist suicide bombing at a U.S. Marine base and learns a new, chemically undetectable bomb material is being consumed. Meanwhile, Riley is forced to make a drastic decision when she finds Gabriel unable to complete a task.
Gabriel and Riley are tasked with finding Kate Anderson a high level CIA analyst who fled the country with sensitive intelligence before it falls into the wrong hands. Meanwhile, Gabriel discovers that Mei Chen is alive and has the capability to be inside his mind.
Riley and Gabriel go on a covert mission in Syria in order to rescue American journalists being held hostage; the truth about Riley's past with her ex-boyfriend is revealed when they are forced to work together.
Gabriel and Riley search for the kidnapped daughter of a senator in Mexico when a Mexican cartel demands he end the sale of U.S. spy satellite in exchange for her safety. Meanwhile, Lillian discovers a connection between the drug cartel and her father.
Gabriel and the CyberCom team head to Texas to help contain an outbreak of a deadly, rapidly spreading virus, but when Gabriel cyber-renders ground zero of the outbreak to isolate who Patient Zero might be, he and the team are shocked to see that the suspect is a criminal believed to have been executed a week earlier.
When Gabriel and CyberCom learn microscopic robots are infecting and killing leading artificial intelligence scientists, they must find who’s delivering boxes containing the malicious nanites before Cassidy is the next target.
When Gabriel's chip is hacked with misinformation, he turns on his own team. Gabriel’s memory is wiped clean after CyberCom is attacked by an aggressive virus, he believes Jin Cong is the good guy and helps him locate a top-secret document.
Gabriel, Riley and Lillian head to San Francisco when the FBI’s Witness Protection database is hacked and someone is blackmailing witnesses to carry out a terrorist attack. The stakes are even higher for Lillian, as her daughter lives in the city.
When Gabriel and Riley search for an infamous hacker known to create cyberworms, they learn their suspect could have been set up and a much more sinister group has plans to target a nuclear reactor in California.
When Gabriel sees himself as the suspected murderer in his crime scene cyber-render, he and Riley must find the mastermind who is framing him. Meanwhile, Lillian is relieved of duty and Tetazoo takes charge with a full-scale manhunt for Gabriel and Riley.